Browsing Faculty of Medicine and Health Sciences ETDs by Title
Now showing items 14-33 of 158
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Baseline sero-survey of rubella virus prevalence in pregnant women in Harare and incidence of rubella in Zimbabwe during 2009-2011 measles outbreak.
(2014-03-17)Rubella virus is a teratogen that may induce foetal death or Congenital Rubella Syndrome (CRS) in the newborn. A baseline sero-survey was carried out in Harare to determine the population susceptible to Rubella virus amongst ... -
Baseline Serological Markers of Hepatitis B Virus Co-Infection in the Development of Antiretroviral Therapy for Africa (DART) Population of Human Immuno Deficiency Virus Infected Patients
(2013-03-06)Hepatitis B virus (HBV) seroprevalence and serology profiles were retrospectively determined for 957 individuals in the Development of Antiretroviral Therapy for Africa (DART), human immunodeficiency virus (HIV) infected ... -
Blood and Urine Lead Levels in Adults Attending Harare Polyclinics
(2013-11)Lead is a toxic environmental pollutant and exposure to it can produce serious adverse health effects in adults and children. There is no safe exposure to lead, however the CDC recommends adult blood lead level (BLL) of < ... -
Breast cancer and HIV: a single institution review of a non-AIDS defining cancer in women in the setting of high HIV prevalence
(2013-08)BACKGROUND The prevalence of HIV infection is high in sub Saharan Africa. However the impact of this high prevalence on breast cancer incidence, pathogenesis, age, stage at presentation, treatment response and toxicity ... -
Co-morbidity of diabetes mellitus and HIV in patients attending the ART clinic Parirenyatwa hospital 2015
(2016-11)Background: Zimbabwe has a double burden of diseases, with HIV epidemic and increased prevalence of diabetes mellitus. Since the roll out of Anti Retroviral Therapy in 2004 at Parirenyatwa OI clinic, Nucleoside Reverse ... -
A comparative evaluation of the performance of the Viroseq HIV-1 genotyping system v2.0 against an in-house assay using specimens from the national HIV drug resistance monitoring survey, in Zimbabwe.
(2013-03-27)This study was carried out to assess the performance of the Viroseq HIV-1 genotyping system v2.0 (Celera, Alameda, California, USA) on Zimbabwean samples at the National Microbiology Reference Laboratory (NMRL) in Harare ... -
Comparison of CD4+ T-Cell changes in response to highly active antiviral therapy (HAART) in adolescents and children enrolled at Parirenyatwa Hospital Family Care Centre (2005-2010) - Secondary Data Analysis
(2013-08)Background In general, there is an increase in CD4 cell count after initiating on HAART. Despite an increasing trend of access to HAART there is a paucity of studies examining the changes in CD4 count over time in Zimbabwe ... -
Comparison of retention in care rates among HIV-infected older persons and young adults on higly active antiretroviral therapy at a tertiary hospital in Harare, Zimbabwe
(2016-05)Objective: To evaluate differences in retention in care rates between older individuals and young adults initiated on HAART and to determine the baseline characteristics that are associated with retention in care. Design: ... -
Controversies surrounding the use of Parathyroid hormone as a marker of bone metabolism in chronic kidney disease(CKD) patients on haemodialysis in Zimbabwe: The way forward
(2013-09)Background The progressive loss of renal function in chronic kidney disease (CKD) necessitates the eventual use of dialysis. Renal Osteodystrophy (ROD) is a serious complication of CKD with diverse and non-specific ... -
Cryptococcal infection in the era of anti-retroviral therapy (ART) amomg HIV infected patients with meningitis at a tertiary hospital in a low - resource setting.
(2016-05)Background: Despite improved access to anti-retroviral therapy (ART) in Africa, HIV-associated cryptococcal meningitis (CM) appears to remain a cause of substantial morbidity and mortality in sub-Saharan African. This study ... -
Delays in performing emergency caesarean sections at Harare maternity hospital and Mbuya Nehanda hospital: Causes and outcomes
(2017-07)Introduction The ideal decision-to-delivery interval (DDI) for emergency Caesarean sections (ECS) quoted in international guidelines is 30minutes. Achieving this DDI is anticipated to improve perinatal outcomes. It has ... -
Determinants of acute malnutrition in children under five years in Harare City Zimbabwe 2011
(2011-08)Background: Malnutrition is associated with 35% of the top five causes of childhood mortality in Zimbabwe. The aim of the study was to identify factors associated with acute malnutrition in Harare City. Methods: A 1:1 age ... -
Determinants of multidrug resistance amongst turberculosis patients in Matabeleland North and Bulawayo Metropolitan provinces, 2013
(2016-05)Introduction: Multidrug resistance tuberculosis is an emerging threat to the management of TB in Zimbabwe. The aim of the study was to investigate the determinants of MDR-TB in Matabeleland North and Bulawayo Metropolitan ... -
Determinants of Post Natal Care Uptake in Bikita District, Masvingo Province, 2011
(2013-06-10)Postnatal care (PNC) gives an opportunity to detect medical problems of the mother and neonate and reduce morbidity and mortality. In 2010 PNC uptake in Bikita was 43%. This study was conducted to determine factors ... -
Determination of omega-3 long chain polyunsaturated fatty acid levels using dried blood spots in Zimbabwean children aged 7 to 9 years
(2013-06)Background: Blood omega-3 long chain-polyunsaturated fatty acids (LC-PUFAs) have been widely studied in children because of the benefits from optimum physical and mental development. Despite these recognized benefits, the ... -
Determining the rate, nature and predictors of adverse drug reactions associated with the use of Highly Active Antiretroviral Therapy (HAART) in a resource limited setting (Zimbabwe)
(2014-05-23)Background: Dilemmas exist between balancing cost and toxicity of antiretroviral therapy (ART) in resource limited settings (RLS). Most pharmacovigilance programmes in RLS are unable to monitor adverse drug reactions (ADRs) ... -
Development toxicity effects of atorvastatin and rosuvastatin in mice
(2016-05)Background: Statins reduce the risk, morbidity and mortality associated with cardiovascular events, and generally considered safe to use but their safety in pregnancy is not known. Statins are considered potentially ... -
Development, safety and efficacy evaluation of actinic damage retarding nano-pharmaceutical treatments in oculocutaneous albinism
(2017-04)Introduction: There are at least 17 000 Persons living with albinism (PLWA) in Zimbabwe. Oculocutaneous albinism (OCA) is a congenital amelanistic pigmentation disorder that affects all known vertebrates and has no known ... -
Distal Hypospadias Repair: Comparison of Snodgrass versus Modified Mathieu Procedures: A Randomized Clinical Trial
(2013-06)Background Hypospadias is defined as the presence of abnormal meatal opening along the ventral aspect of the penile shaft or into the perineum. Of the many operative techniques for distal hypospadias repair, two techniques ... -
The effect of a single low dose propofol at the end of the operation in reducing post operative nausea and vomiting ( PONV) in women undergoing laparoscopic gynaecological surgery at Parirenyatwa hospital.
(2013-06-26)Objectives To determine the effectiveness of single low dose propofol in reducing PONV in women undergoing laparoscopic gynaecological surgery. To describe factors associated with nausea and vomiting in women undergoing ...
