Background: Pain is a prevalent symptom in cancer patients, affecting up to 50% of patients undergoing active cancer treatment and up to 90% of those with advanced disease. Although adequate relief can be achieved in the ...

Pharmacogenomics is today’s hot topic in biotechnology. In 1996 the word did not even exist; now international pharmacogenomics meetings are held monthly, and articles appear weekly in scientific journals ind the popular ...

Nitric oxide (NO) is a unique, endogenous regulatory molecule that is involved in a wide variety of physiological processes in multiple organ systems. This simple gas functions as a cellular messenger in a broad range of ...

The impact of ischaemic heart disease on the burden of cardiovascular disease continues to escalate worldwide. • although international statistics suggest a levelling off in Western world, in the less industrialised parts ...

Membranous nephropathy (MN), the most common cause of nephrotic syndrome in adults, is usually idiopathic, with an identifiable cause in only about 20% of cases.1 Causes of secondary MN include various auto-immune diseases, ...

Many people could define with ease the job of a cardiologist, a paediatrician or an obstetrician. However, only a few would have any clear idea of how a clinical pharmacologist might fill a day. Indeed, within the medical ...