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    Iron Overload

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    Date
    1972-01
    Author
    Buchanan, W. M.
    Type
    Article
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    Abstract
    Recent investigations,' have suggested that the average amount of' usable storage iron in a normal male is about lg, values above l,5g being unusual, and above 2,2g constitute iron overload. (Weinfeld, 1970). In males about 0,4g of storage iron is present in liver. Storage iron exists in tissues in two forms, viz., as ferritin which is soluble in water and does not stain with Prussian blue, and as haemosiderin which is insoluble and does stain with this reagent. At concentrations of less than approximately 0,25mg/g wet weight of tissue the iron is in the form of ferritin and so cannot be demonstrated histologically; above this concentration granules of haemosiderin are formed and these can be seen histologically. In both of these compounds iron is in the form of a colloidal complex.
    Full Text Links
    BUCHANAN, W. M. (1972) Iron Overload, CAJM vol. 18, no.2. Harare (formerly Salisbury), Avondale; CAJM.
    0008-9176
    http://opendocs.ids.ac.uk/opendocs/handle/123456789/5127
    URI
    http://hdl.handle.net/10646/1930
    Publisher
    Central African Journal of Medicine (CAJM), University of Zimbabwe (formerly University College of Rhodesia.)
    Subject
    Health
    Nutrition
    xmlui.dri2xhtml.METS-1.0.item-rights
    http://creativecommons.org/licenses/by-nc-nd/3.0/

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