Show simple item record

dc.creatorMakuyana, D
dc.creatorGomo, Zar
dc.creatorMunyombwe, T.
dc.creatorMatenga, J.A.
dc.creatorHakim, J.G.
dc.identifierMakuyana, D [et al] (2004) Metabolic Syndrome Disorders In Urban Black Zimbabweans With Type 2 Diabetes mellitus, CAJM vol. 50, no.3. Harare, Avondale: CAJM
dc.description.abstractObjective: The main aim of the study was to determine the prevalence of metabolic syndrome disorders and their interrelations in black Zimbabwean type 2 diabetic patients. Study Design: Prospective cross sectional study. Setting: Outpatient diabetic clinics at Harare and Parirenyatwa tertiary hospitals. Main Outcome Measures: We recruited 109 adult diabetic subjects attending a tertiary hospital Diabetic Clinic. Anthropometric and metabolic parameters were measured by standard methods. Eighty percent of the patients were hypertensive, 32% dyslipidaemic, 32% obese, 50% hyperinsulinaemic, 61% had poor • glycaemic control and 43% of the participants had the metabolic syndrome. The means of BMI and triglycerides were significantly different in hyperinsulinaemic versus non-hyperinsulinaemic patients (p<0.001 and 0.041 respectively), and diastolic blood pressure was significantly raised in the obese group (p=0.043). The following significant associations were observed, hyperinsulinaemia with the metabolic syndrome (odds ratio=3.9, p<0.001) as well with obesity (odds ratio=4.8, p<0.001), however, only a weak association was observed between hypertension and hyperinsulinaemia (odds ratio=2.5, p=0.064). Patients exhibiting three metabolic disorders (dyslipidaemia, hypertension and obesity) were five times more likely to be hyperinsulinaemic (p=0.025) and hypertensive patients were almost three times more likely to, be hyperinsulinaemic. Conclusion: In comparison to their counterparts from certain ethnic groups, this urban diabetic population is also burdened with a variety of metabolic disorders which are risk factors for coronary artery disease. In this population, hyperinsulinaemia has a relatively weak association with hypertension and the relationship between obesity versus diastolic blood pressure as well as hypertriglyceridaemia versus serum insulin levels requires further investigation.
dc.publisherCentral African Journal of Medicine (CAJM), University of Zimbabwe
dc.rightsUniversity of Zimbabwe
dc.titleMetabolic Syndrome Disorders In Urban Black Zimbabweans With Type 2 Diabetes Mellitus

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record