Department of Clinical Pharmacology and Toxicology

Recent Submissions

  • Current treatment and future prospects for the management of acute coronary syndromes 

    Bhagat, K. (University of Zimbabwe, College of Health Sciences, 1999)
    The impact of ischaemic heart disease on the burden of cardiovascular disease continues to escalate worldwide. • although international statistics suggest a levelling off in Western world, in the less industrialised parts ...

  • Oh no, not Nitric Oxide! 

    Bhagat, K. (University of Zimbabwe, College of Health Sciences, 1999)
    Nitric oxide (NO) is a unique, endogenous regulatory molecule that is involved in a wide variety of physiological processes in multiple organ systems. This simple gas functions as a cellular messenger in a broad range of ...

  • Pharmacogenomics: today, tomorrow and beyond 

    Bhagat, K. (University of Zimbabwe, College of Health Sciences, 1999)
    Pharmacogenomics is today’s hot topic in biotechnology. In 1996 the word did not even exist; now international pharmacogenomics meetings are held monthly, and articles appear weekly in scientific journals ind the popular ...

  • Trends in cancer pain management 

    Bhagat, K.; Chinyanga, H. M. (University of Zimbabwe, College of Health Sciences, 2000)
    Background: Pain is a prevalent symptom in cancer patients, affecting up to 50% of patients undergoing active cancer treatment and up to 90% of those with advanced disease. Although adequate relief can be achieved in the ...

  • Hardly a harmless analgesic 

    Bhagat, K.; Tisocki, K. (University of Zimbabwe, College of Health Sciences, 1999)
    Membranous nephropathy (MN), the most common cause of nephrotic syndrome in adults, is usually idiopathic, with an identifiable cause in only about 20% of cases.1 Causes of secondary MN include various auto-immune diseases, ...

  • Clinical pharmacologist wanted - where? 

    Bhagat, K.; Tisocki, K. (University of Zimbabwe, College of Health Sciences, 1999)
    Many people could define with ease the job of a cardiologist, a paediatrician or an obstetrician. However, only a few would have any clear idea of how a clinical pharmacologist might fill a day. Indeed, within the medical ...

  • Factors influencing treatment failure in HIV positive adult patients on first line antiretroviral therapy 

    Chawana, T.D.; Reid, A.; Bwakura, T.; Gavi, S.; Nhachi, C.F.B. (University of Zimbabwe, College of Health Sciences, 2014)
    Background: Risk factors for treatment failure in HIV positive adults have not been studied extensively in Zimbabwe. Aim: To investigate socio-demographic, psychosocial and antiretroviral drug related factors as possible ...

  • Factors influencing treatment failure in HIV positive adult patients on first line antiretroviral therapy 

    Chawana, T.D.; Reid, A.; Bwakura, T.; Gavi, S.; Nhachi, C.F.B. (University of Zimbabwe, College of Health Sciences, 2014)
    Background: Risk factors for treatment failure in HIV positive adults have not been studied extensively in Zimbabwe. Aim: To investigate socio-demographic, psychosocial and antiretroviral drug related factors as possible ...

  • Levels of chromium in Zimbabwean foods and its importance in carbohydrate metabolism 

    Nyazema, N.Z.; Sox, R. (University of Zimbabwe, College of Health Sciences, 1986)
    Staple foods eaten by Zimbabweans were collected and analysed for their chromium content. Organic matter was destroyed by a wet oxidation procedure using concentrated sulphuric and nitric acids. The food digest was directly ...

  • Theophylline usage in patients with acute asthma presenting to a Central Hospital 

    Mutandwa, P.; Neill, P. (University of Zimbabwe, College of Health Sciences, 1987)
    A survey was conducted to investigate the medication taken by asthmatics presenting to a casualty department, particularly with reference to theophylline. Serum levels of theophylline were measured to give an indication ...