Browsing Biochemistry Staff Publications by Author "Appleby, Laura J."
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Group 2 Innate Lymphoid Cell Proportions Are Diminished in Young Helminth Infected Children and Restored by Curative Antihelminthic Treatment
Nausch, Norman; Appleby, Laura J.; Sparks, Alexandra M.; Midzi, Nicholas; Mduluza, Takafira; Mutapi, Francisca (PLoS, 2015-03-20)Group 2 Innate lymphoid cells (ILC2s) are innate cells that produce the TH2 cytokines IL-5 and IL-13. The importance of these cells has recently been demonstrated in experimental models of parasitic diseases but there is ... -
Proportions of CD41 memory T cells are altered in individuals chronically infected with Schistosoma haematobium
Bourke, Claire D.; Appleby, Laura J.; Rujeni, Nadine; Lantz, Olivier; Trottein, François; Midzi, Nicholas; Nausch, Norman; Mduluza, Takafira; Mutapi, Francisca (Nature Publishing Group, 2012-06-26)Characterisation of protective helminth acquired immunity in humans or experimental models has focused on effector responses with little work conducted on memory responses. Here we show for the first time, that human ...