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4-Aminoquinoline Prophylaxis of Malaria amongst Semi-Immune African School Children

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dc.creator Clyde, D.F.
dc.creator Shute, G.T. 2015-07-21T15:20:16Z 2015-12-08T10:55:27Z 2015-07-21T15:20:16Z 2015-12-08T10:55:27Z 2015-07-21T15:20:16Z 1957-12
dc.identifier Clyde, D.F. & Shute, G.T. (1957) 4-Aminoquinoline Prophylaxis of Malaria amongst Semi-Immune African School Children. CAJM vol. 3, no. 12. (pp. 496-498.) UZ (formerly University College Rhodesia), Harare (formerly Salisbury.) : Faculty of Medicine.
dc.identifier 0379-0622
dc.description.abstract Drugs used for the prophylaxis of malaria are generally recommended in doses sufficient to suppress the disease in persons without immunity, these amounts being considerably in excess of those required for the protection of indigenous inhabitants of malarious districts. Information is not generally available concerning the smallest useful doses of the 4-aminoquinoline series of suppressives amongst school children who possess a high degree of premunition, because treatment varies from place to place in relation to differing degrees of immunity and infection risk. It is the purpose of the trials described in this report to demonstrate dosages of amodiaquine and chloroquine just sufficient to prevent overt parasitaemia in children aged 6 to 15 years native to areas of holoendemic malaria transmission in East and Central Africa where Plasmodium falciparum predominates.
dc.language en
dc.publisher Faculty of Medicine, Central African Journal of Medicine (CAJM), University College of Rhodesia (now University of Zimbabwe)
dc.rights University of Zimbabwe (UZ) (formerly University College of Rhodesia)
dc.subject Children and Youth
dc.subject Health
dc.title 4-Aminoquinoline Prophylaxis of Malaria amongst Semi-Immune African School Children
dc.type Article

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